Various studies using physical, chemical, and biological parameters have shown that the Babon River is lightly to heavily polluted. Using the Babon River as a raw water source for drinking water requires better and stricter management to control river pollution. This study aimed to determine the pollution load, assimilation capacity, and pollution status of the Babon River using TSS, TDS, nitrate, phosphate, total phosphate, metals Cd, Cr, and Pb. Water sampling was conducted three times a year at two-month intervals at seven stations representing the upstream, middle, and downstream parts of the river. This study showed that the pollution load of Babon River exceeded the assimilation capacity for TSS, nitrates, Cd, Cr, and Pb. For TSS, phosphate, and total phosphate, the pollution load was within the river's assimilation capacity. The water pollution index of the Babon River ranged from 3.884 to 5.395. This indicates that the Babon River was polluted at mild to moderate levels from the upstream to the downstream regions.