A laser fluorimetric technique was used to measure the amount of uranium present in samples of groundwater from the Balod district, Chhattisgarh, central India. For this purpose, we collected twenty-nine water samples from different villages in the Balod district, Chhattisgarh from September 2022 to June 2023. Here, the concentration of uranium in the sample of water ranges from 0.10 to 66.7(µg/l). A maximum number of samples had uranium contamination levels below the acceptable limit (30 µg/l), except for Siwani village (66.7µg/l), as approved by the WHO. The USEPA recommendations were used to determine the chemical risk ( Non-carcinogenic) and excess lifetime carcinogenic risk (ECR) caused by groundwater consumption. The allowed excess lifetime cancer risk ( ELCR) value of 1.0´10-4was found to be exceeded in a few water samples by the risk of cancer resulting from drinking water. The LADD value of 18 % and HQ value of 24% of the water sample exceed the permissible limit indicating a high risk of chemical poisoning. In this analysis, we found that the area's uranium's chemical toxicity may be the cause of non-carcinogenic health problems, but eventually, there is no Carcinogenic (radiological) risk to people.