Owing to the changes in human lifestyle and resource deterioration impelled by rapid population growth and unsustainable industrialization, waste management has emerged as an extensive contrivance for human welfare and environmental prosperity. Unmanaged waste impacts both rich and poor hurting their economy and environment. Organic waste, being the largest component of MSW in developing countries, can be developed into a valuable resource by utilizing microorganisms. A brief repository about the exertion of microbes for sustainable degradation of organic waste was presented in this article describing the ways how organic waste can be transformed in marketable asset generating remarkable profits.